Raffaella’s Literature Update
Ref. CIOMS Special Newsletter “Fighting antimicrobial resistance”, November 2022
Antimicrobial Resistance (AMR), including bacterial resistance to antibiotics, is among the major concerns for global health. This short newsletter of the Council for International Organizations of Medical Sciences (CIOMS) provides an overview of the situation, and a list of key-references for further reading. The document may be of interest for many of us, e.g., for personal scientific update or for feeding/updating our teaching materials (figures and visuals are particularly good).
You will find data on the global AMR burden, drivers and impact, and an overview of the One Health approach. Furthermore, as “the R&D pipeline has not kept pace with the growing demand for new products”, the section on “Innovation” discusses the need of new treatments (traditional antibacterials, but also non-traditional ones such as bacteriophages, microbiome-modulating agents, antibodies or immunomodulating agents), new vaccines and new diagnostics. There is also an interesting analysis of the new private, public and not-for-profit funders of R&D.
To conclude, I would like to copy-paste an important paragraph from the document (the underlined is mine): “The pandemic of antimicrobial resistance must be fought with global public health needs in mind. Different public-private partnership models may be employed to raise the funding and human resources that are required to develop products and keep them on the market. In any such partnership, government input and oversight are needed to maintain a public health focus. Non-profit organisations like GARDP, that mobilize the support of governments and foundations all along the development process, have a good chance of success. Their approach may encourage governments to create incentives for public and private actors to ensure that effective antimicrobials will reach all those who need them”.
Have a nice reading,